Heat Shock Chaperone 90 Dynamics

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The supplemental movie is a schematic animation of the dynamics of Hsp90 about 5 times speed up.
The first part is without nucleotide, then with ATP bound, and finally in the ADP bound state.
The rate constants and further information are given in (1).
Movie made by W. Schürmann, Medienlabor, TUM


(1) C. Ratzke, M. Mickler, B. Hellenkamp, J. Buchner and T. Hugel,
„Dynamics of heat shock protein 90 C-terminal dimerization is an important part of its conformational cycle”
PNAS, Online Early Edition in the week of August 23, 2010