Bausch Group

Understanding complex biomaterials on a fundamental physical basis is an integral challenge of future biophysical research. This challenge can be addressed by the concerted application of new experimental tools of soft condensed matter physics to living cells and bio-mimetic model systems.

In our group we concentrate on the one hand on developing new physical tools to address the underlying complexity and mechanisms and on the other hand on developing new biomaterials for applications ranging from biomedicine to functional food.

 

Topology and Dynamics of Active Nematic Vesicles

We have implemented a minimalistic model of of a shape-changing cell that moves on its own. Basically our synthetic biology approach combines only a few molecular ingredients: microtubule polymers and kinesin motors are encapsulated into a vesicle by a lipid bilayer. We observe a rich variety of morphologies that can be explained by geometrical and topological effects on the nematic microtubule cortex.

READ MORE ON VESICLE IN MOTION

Artwork, (c) C. Hohmann, Nano Initiative Munich

Latest Publications

 

C. A. Weber, R. Suzuki, V. Schaller, I. S. Aranson, A. R. Bausch and E. Frey (2015)
Random Bursts Determine Dynamics of Active Filaments
PNAS Early Edition, doi: 10.1073/pnas.1421322112 Link:  [download]


R. Suzuki, C. A. Weber, E. Frey and A. R. Bausch (2015)
Polar pattern formation in driven filament systems requires non-binary particle collisions
Nature Physics, DOI: 10.1038/NPHYS3423 Link:  [download] [see also N&V]



Research Areas

Complex Microfluidics and Biomaterials
Cytoskeleton and Biopolymer Networks
Pattern Formation
Nanoscopy
Completed Projects