Rief Group

Prof. Dr. Matthias Rief

Proteins are fascinating examples of self-organized molecular machines. Without any help a polypeptide strand can fold into functional threedimensional structures. We are interested in studying the function and folding process of proteins on the single molecule level. Examples are single molecule folding/unfolding studies or the motility of molecular motors in optical traps.

Latest Publications

 

Zoldak. G., and Rief, M. (2013)
Force a single molecule probe of multidimensiional protein energy landscapes
Curr Opin Struct Biol. Link:  [download]


L. Rognoni, J. Stigler, B. Pelz, J. Ylänne, M. Rief (2012)
Dynamic force sensing of filamin revealed in single-molecule experiments
PNAS, 109, 19679-19684



24.05.2013, 13:00 in Room ph127:

Jürgen Bosch; Johns Hopkins University; Johns Hopkins Malaria Research Institute; Baltimore; USA: "The Plasmodium falciparum Glideosome - a Novel Drug Target"

Research Areas

Protein Folding
Protein-Protein Interactions
Molecular Motors
Cytoskeletal Mechanics