Rief Group

Prof. Dr. Matthias Rief

Proteins are fascinating examples of self-organized molecular machines. Without any help a polypeptide strand can fold into functional threedimensional structures. We are interested in studying the function and folding process of proteins on the single molecule level. Examples are single molecule folding/unfolding studies or the motility of molecular motors in optical traps.

Latest Publications

 

KM Tych, M. Jahn, H. Girstmair, T. Hugel, J. Buchner, M. Rief (2018)
Unravelling the Mechanics of a Molecular Chaperone
Biophysical Journal 114 (3), 552a Link:  [download]


M Jahn, K Tych, H Girstmair, M Steinmaßl, T Hugel, M Rief (2018)
Folding and Domain Interactions of Three Orthologs of Hsp90 Studied by Single-Molecule Force Spectroscopy
Structure 26 (1), 96-105 Link:  [download]





Research Areas

Protein Folding
Molecular Machines
Cytoskeletal Mechanics
Optical Trap Setup