Rief Group

Prof. Dr. Matthias Rief

Proteins are fascinating examples of self-organized molecular machines. Without any help a polypeptide strand can fold into functional threedimensional structures. We are interested in studying the function and folding process of proteins on the single molecule level. Examples are single molecule folding/unfolding studies or the motility of molecular motors in optical traps.

Latest Publications


M. Grison, U. Merkel, J. Kostian, Kr. Djinovic-Carugo, M. Rief (2017)
alpha-Actinin/titin interaction: A dynamic and mechanically stable cluster of bonds in the muscle Z-disk

F. Kilchherr, Chr. Wachauf, B. Pelz, M. Rief, M. Zacharias, H. Dietz (2016)
Single-molecule dissection of stacking forces in DNA
Science, Vol. 353, Issue 6304 Link: science.sciencemag.org/content/353/6304/aaf5508

Research Areas

Protein Folding
Protein-Protein Interactions
Molecular Motors
Cytoskeletal Mechanics