Rief Group

Prof. Dr. Matthias Rief

Proteins are fascinating examples of self-organized molecular machines. Without any help a polypeptide strand can fold into functional threedimensional structures. We are interested in studying the function and folding process of proteins on the single molecule level. Examples are single molecule folding/unfolding studies or the motility of molecular motors in optical traps.

Latest Publications

 

J. Stigler, F. Ziegler, A. Gieseke, J. C. M. Gebhardt and M. Rief (2011)
The complex folding network of single calmodulin molecules
Science, 334, 512-516


F. Berkemeier, M. Bertz, S. Xiao, N. Pinotsis, M. Wilmanns, F. Grater, M. Rief (2011)
Fast-folding {alpha}-helices as reversible strain absorbers in the muscle protein myomesin
PNAS 34:14139-44




Research Areas

Protein Folding
Protein-Protein Interactions
Molecular Motors
Cytoskeletal Mechanics